There is a big difference in fertilizers.

We inadvertently performed a little test on which fertilizers are better; chemical fertilizer, a little horse manure, or a lot of horse manure.
Our adult son works at a fertilizer co-op that supplies the potato farmers around here with chemical fertilizer, and he put it on two rows of his corn.
We planted some corn with 4 inches of manure tilled in.  And our 11 year old son planted his corn on what was a pile of manure tilled in.
Our 11 year old's grew the tallest.  The corn we planted in 4 inches was the next tallest.  And the corn that was fertilized with chemical fertilizer was half as tall.

Corn in the garden

Corn near the grapes